Can Butalbital Cause A Rash Can Certain Medicines Cause A Female To Have Sore Breasts And Spot Bleed Before Her Period?

Can certain medicines cause a female to have sore breasts and spot bleed before her period? - can butalbital cause a rash

I am taking medication for back pain with radiculopathy, tension headaches and migraines. I take the following medications: oral contraceptives, Nortryptyline 75 mg Maxalt MLT 10 mg and 50 mg Tramadol Butalbital / APAP / Caffeine tablets.